anti-ACTR1A + ACTR1B antibody
CAT.NO. : ARG41179
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概述
产品描述 | Rabbit Polyclonal antibody recognizes ACTR1A + ACTR1B |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ACTR1A + ACTR1B |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 187-376 of Human ACTR1A (NP_005727.1). |
偶联标记 | Un-conjugated |
別名 | Alpha-centractin; Actin-RPV; Arp1A; Centractin; Centrosome-associated actin homolog; CTRN1; ARP1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse spleen | ||||
实际分子量 | 45 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | ACTR1A |
全名 | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
背景介绍 | This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008] |
生物功能 | Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. [UniProt] |
细胞定位 | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cell cortex. [UniProt] |
预测分子量 | 43 kDa |
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