anti-ADAM28 antibody
CAT.NO. : ARG43658
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概述
产品描述 | Rabbit Polyclonal antibody recognizes ADAM28 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ADAM28 |
抗原物种 | Human |
抗原 | Recombinant fragment within a.a. 190-450 of Human ADAM28. |
偶联标记 | Un-conjugated |
Protein Full name | Disintegrin and metalloproteinase domain-containing protein 28 |
別名 | Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; eMDC II; EC 3.4.24.-; MDC-L; MDCL; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; Disintegrin and metalloproteinase domain-containing protein 28; eMDCII; ADAM 28 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
实际分子量 | 87, 61 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS, 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
浓度 | Batch dependent |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q9JLN6 Mouse Disintegrin and metalloproteinase domain-containing protein 28 Swiss-port # Q9UKQ2 Human Disintegrin and metalloproteinase domain-containing protein 28 |
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基因名称 | ADAM28 |
全名 | ADAM metallopeptidase domain 28 |
背景介绍 | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
生物功能 | May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. [UniProt] |
细胞定位 | Cell membrane; Membrane; Secreted |
预测分子量 | 87 kDa |
翻译后修饰 | Pro-domain removal and maturation may be, at least in part, autocatalytic. [UniProt] |
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