anti-AHSG antibody
CAT.NO. : ARG55425
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概述
产品描述 | Rabbit Polyclonal antibody recognizes AHSG |
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反应物种 | Hu, Ms |
应用 | FACS, ICC/IF, IHC-P, IP, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | AHSG |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 247-276 (C-terminus) of Human AHSG. |
偶联标记 | Un-conjugated |
別名 | A2HS; Alpha-2-HS-glycoprotein; HSGA; Ba-alpha-2-glycoprotein; AHS; FETUA; Alpha-2-Z-globulin; Fetuin-A |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
阳性对照 | Human liver |
属性
形式 | Liquid |
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纯化 | Purification with Protein A and immunogen peptide. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide |
抗菌剂 | 0.09% (W/V) Sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | AHSG |
全名 | alpha-2-HS-glycoprotein |
背景介绍 | Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008] |
生物功能 | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. [UniProt] |
细胞定位 | Secreted. |
研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody |
预测分子量 | 39 kDa |
翻译后修饰 | Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4; N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor). |
检测图片 (4)
ARG55425 anti-AHSG antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG55425 anti-AHSG antibody (green). DAPI (blue) for nuclear staining.
ARG55425 anti-AHSG antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatocarcinoma stained with ARG55425 anti-AHSG antibody.
ARG55425 anti-AHSG antibody WB image
Western blot: 35 µg of Human liver lysate stained with ARG55425 anti-AHSG antibody at 1:1000 dilution.
ARG55425 anti-AHSG antibody FACS image
Flow Cytometry: HepG2 cells stained with ARG55425 anti-AHSG antibody (right histogram) or without primary antibody control (left histogram), followed by incubation with FITC labelled secondary antibody.
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