anti-AKR1C3 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG63695
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes AKR1C3 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AKR1C3 |
| 抗原物种 | Human |
| 抗原 | CFASHPNYPYSDEY |
| 偶联标记 | Un-conjugated |
| 別名 | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Testosterone 17-beta-dehydrogenase 5; EC 1.1.1.239; Dihydrodiol dehydrogenase 3; HA1753; EC 1.1.1.112; 3-alpha-HSD type II, brain; Chlordecone reductase homolog HAKRb; DD3; Indanol dehydrogenase; EC 1.1.1.188; HSD17B5; Aldo-keto reductase family 1 member C3; DDX; 17-beta-hydroxysteroid dehydrogenase type 5; hluPGFS; 3-alpha-HSD type 2; EC 1.3.1.20; EC 1.1.1.357; Prostaglandin F synthase; HAKRe; 3-alpha-hydroxysteroid dehydrogenase type 2; EC 1.1.1.64; DD-3; 17-beta-HSD 5; HAKRB; EC 1.-.-.-; Dihydrodiol dehydrogenase type I; PGFS |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P42330 Human Aldo-keto reductase family 1 member C3 |
|---|---|
| 背景介绍 | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| 研究领域 | Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 37 kDa |
检测图片 (2)
ARG63695 anti-AKR1C3 antibody WB image
Western Blot: human breast lysate (35 µg protein in RIPA buffer) stained with ARG63695 anti-AKR1C3 antibody at 0.03 µg/ml dilution.
ARG63695 anti-AKR1C3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63695 anti-AKR1C3 antibody at 5 µg/ml dilution followed by AP-staining.
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