anti-ALAS1 antibody
CAT.NO. : ARG58186
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概述
产品描述 | Rabbit Polyclonal antibody recognizes ALAS1 |
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反应物种 | Hu |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ALAS1 |
抗原物种 | Human |
抗原 | Synthetic peptide derived from Human Alas1. |
偶联标记 | Un-conjugated |
別名 | Delta-aminolevulinate synthase 1; 5-aminolevulinic acid synthase 1; ALASH; Delta-ALA synthase 1; ALAS3; 5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS-H; MIG4; ALAS; EC 2.3.1.37 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | HepG2 | ||||||
实际分子量 | ~ 71 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P13196 Human 5-aminolevulinate synthase, nonspecific, mitochondrial |
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基因名称 | ALAS1 |
全名 | 5'-aminolevulinate synthase 1 |
背景介绍 | This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015] |
细胞定位 | Mitochondrion matrix. [UniProt] |
预测分子量 | 71 kDa |
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