anti-ALDH6A1 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes ALDH6A1
  • 反应物种: Hu
  • 应用: ICC/IF, IHC-P
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 147CT8.3.4
  • 同位型: IgG1, kappa
  • 靶点名称: ALDH6A1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG40467
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes ALDH6A1
反应物种Hu
应用ICC/IF, IHC-P
宿主Mouse
克隆Monoclonal
克隆号147CT8.3.4
同位型IgG1, kappa
靶点名称ALDH6A1
抗原物种Human
抗原Human ALDH6A1 recombinant protein.
偶联标记Un-conjugated
別名MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; EC 1.2.1.18; EC 1.2.1.27; MMSADHA
应用说明
应用建议
应用推荐稀释比
ICC/IF1:25
IHC-P1:25
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide.
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4329 Human ALDH6A1

Swiss-port # Q02252 Human Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

基因名称ALDH6A1
全名aldehyde dehydrogenase 6 family, member A1
背景介绍This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
生物功能Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA. [UniProt]
细胞定位Mitochondrion. [UniProt]
预测分子量58 kDa
检测图片 (2)
  • ARG40467 anti-ALDH6A1 antibody ICC/IF image

    Immunofluorescence: MCF7 cells stained with ARG40467 anti-ALDH6A1 antibody (green) at 1:25 dilution. DAPI (blue) for nuclear staining. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).

  • ARG40467 anti-ALDH6A1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver tissue stained with ARG40467 anti-ALDH6A1 antibody at 1:25 dilution.

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