anti-alpha Fetoprotein antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 偶联标记:
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Brand:
CAT.NO. : ARG44618
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes alpha Fetoprotein |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | alpha Fetoprotein |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | AFP; Alpha Fetoprotein; Alpha-Fetoprotein; HPAFP; FETA; Alpha-1-Fetoprotein; Alpha-Fetoglobulin; AFPD |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O14727 Human Apoptotic protease-activating factor 1 |
|---|---|
| 基因名称 | AFP |
| 全名 | Alpha Fetoprotein |
| 背景介绍 | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019] |
| 生物功能 | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 69 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein, Sulfation. [UniProt] |
检测图片 (3)
ARG44618 anti-alpha Fetoprotein antibody IHC-P image
Immunohistochemistry: Human testis stained with ARG44618 anti-alpha Fetoprotein antibody at 2 µg/mL dilution.
ARG44618 anti-alpha Fetoprotein antibody WB image
Western blot: Human plasma stained with ARG44618 anti-alpha Fetoprotein antibody at 1 µg/mL dilution.
ARG44618 anti-alpha Fetoprotein antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg ARG44618 anti-alpha Fetoprotein antibody.
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