anti-ALS2 / Alsin antibody
CAT.NO. : ARG63284
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概述
产品描述 | Goat Polyclonal antibody recognizes ALS2 / Alsin |
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反应物种 | Hu |
预测物种 | Ms, Rat, Cow, Dog |
应用 | IHC-P |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ALS2 / Alsin |
抗原物种 | Human |
抗原 | LKACYYQIQREKLN |
偶联标记 | Un-conjugated |
別名 | Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Alsin; ALSJ; IAHSP; Amyotrophic lateral sclerosis 2 protein; ALS2CR6; PLSJ |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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背景介绍 | The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
研究领域 | Neuroscience antibody |
预测分子量 | 184 kDa |
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