anti-ALS2 / Alsin antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes ALS2 / Alsin
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow, Dog
  • 应用: IHC-P
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ALS2 / Alsin
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63284
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes ALS2 / Alsin
反应物种Hu
预测物种Ms, Rat, Cow, Dog
应用IHC-P
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称ALS2 / Alsin
抗原物种Human
抗原LKACYYQIQREKLN
偶联标记Un-conjugated
別名Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Alsin; ALSJ; IAHSP; Amyotrophic lateral sclerosis 2 protein; ALS2CR6; PLSJ
应用说明
应用建议
应用推荐稀释比
IHC-P3 - 5 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 57679 Human ALS2

Swiss-port # Q96Q42 Human Alsin

背景介绍The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
研究领域Neuroscience antibody
预测分子量184 kDa
检测图片 (1)
  • ARG63284 anti-ALS2 / Alsin antibody IHC-P image

    Immunohistochemistry: Paraffin embedded Human Cortex. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63284 anti-ALS2 / Alsin antibody at 3.8 µg/ml dilution followed by AP-staining.

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