anti-ANKRD1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ANKRD1
  • 反应物种: Hu, Ms, Rat
  • 预测物种: Bov, Chk, Pig, Rb
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ANKRD1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG66456
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ANKRD1
反应物种Hu, Ms, Rat
预测物种Bov, Chk, Pig, Rb
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ANKRD1
抗原物种Human
抗原KLH-conjugated synthetic peptide within the C-terminal region of Human ANKRD1.
偶联标记Un-conjugated
別名bA320F15.2; CVARP; ALRP; CARP; Cardiac ankyrin repeat protein; Cytokine-inducible nuclear protein; Cytokine-inducible gene C-193 protein; C-193; MCARP; Ankyrin repeat domain-containing protein 1
应用说明
应用建议
应用推荐稀释比
IHC-P1:100 - 1:200
WB1:500 - 1:1000
应用说明IHC-P: Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量40 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol.
抗菌剂0.01% Sodium azide
稳定剂30% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 107765 Mouse ANKRD1

GeneID: 27063 Human ANKRD1

GeneID: 27064 Rat ANKRD1

基因名称ANKRD1
全名ankyrin repeat domain 1 (cardiac muscle)
背景介绍The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008]
生物功能May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. [UniProt]
细胞定位Nucleus. [UniProt]
预测分子量36 kDa
检测图片 (2)
  • ARG66456 anti-ANKRD1 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human lymph node. Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). The section was then incubated with ARG66456 anti-ANKRD1 antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

  • ARG66456 anti-ANKRD1 antibody WB image

    Western blot: HeLa, Jurkat, NIH/3T3 and H9C2 whole cell lysates stained with ARG66456 anti-ANKRD1 antibody.

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