anti-AP1M2 antibody
CAT.NO. : ARG41196
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概述
产品描述 | Rabbit Polyclonal antibody recognizes AP1M2 |
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反应物种 | Hu, Ms |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | AP1M2 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 164-423 of Human AP1M2 (NP_005489.2). |
偶联标记 | Un-conjugated |
別名 | HSMU1B; Golgi adaptor HA1/AP1 adaptin mu-2 subunit; MU-1B; Mu-adaptin 2; AP-mu chain family member mu1B; mu2; Adaptor-related protein complex 1 subunit mu-2; Clathrin assembly protein complex 1 mu-2 medium chain 2; MU1B; Mu1B-adaptin; AP-1 complex subunit mu-2; AP1-mu2; Adaptor protein complex AP-1 subunit mu-2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Mouse kidney | ||||||
实际分子量 | 48 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | AP1M2 |
全名 | adaptor-related protein complex 1, mu 2 subunit |
背景介绍 | This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
生物功能 | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. [UniProt] |
细胞定位 | Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. [UniProt] |
预测分子量 | 48 kDa |
翻译后修饰 | Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. [UniProt] |
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