anti-APLP1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG43894
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes APLP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | APLP1 |
| 抗原物种 | Human |
| 抗原 | Human APLP1 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Amyloid beta precursor like protein 1 |
| 別名 | APLP1; Amyloid Beta Precursor Like Protein 1; APLP; Amyloid Beta (A4) Precursor-Like Protein 1; Amyloid-Like Protein 1; Amyloid Precursor-Like Protein 1; APLP-1 |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | APLP1 |
| 全名 | Amyloid Beta Precursor Like Protein 1 |
| 背景介绍 | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. |
| 生物功能 | Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. |
| 细胞定位 | Cell membrane, Cytoplasm, Membrane |
| 预测分子量 | 72 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (4)
ARG43894 anti-APLP1 antibody WB image
Western blot: SH-SY5Y and U-87MG stained withARG43894anti-APLP1 antibody at 0.5 μg/mL dilution.
ARG43894 anti-APLP1 antibody FACS image
Flow Cytometry: SiHa cells stained withARG43894 anti-APLP1 antibody (blue) at 1 μg/1x10^6 cells dilution.
ARG43894 anti-APLP1 antibody WB image
Western blot: Mousebrain stained withARG43894 anti-APLP1 antibody at 0.5 μg/mL dilution.
ARG43894 anti-APLP1 antibody WB image
Western blot: Rat brain and Rat liver stained withARG43894 anti-APLP1 antibody at 0.5 μg/mL dilution.
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