anti-APOBEC3G antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes APOBEC3G
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: APOBEC3G
  • 抗原物种: Human
  • 抗原: C-DEHSQDLSGRLR
  • Brand:
CAT.NO. : ARG64741
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes APOBEC3G
反应物种Hu
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称APOBEC3G
抗原物种Human
抗原C-DEHSQDLSGRLR
偶联标记Un-conjugated
別名ARP-9; APOBEC-related cytidine deaminase; Deoxycytidine deaminase; APOBEC-related protein; dJ494G10.1; DNA dC->dU-editing enzyme APOBEC-3G; CEM-15; CEM15; ARCD; ARP9; APOBEC-related protein 9; EC 3.5.4.-; A3G; bK150C2.7; MDS019
应用说明
应用建议
应用推荐稀释比
IHC-P2.5 µg/ml
WB0.5 - 1.5 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 60489 Human APOBEC3G

Swiss-port # Q9HC16 Human DNA dC->dU-editing enzyme APOBEC-3G

背景介绍This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Jul 2008]
研究领域Gene Regulation antibody; Immune System antibody; Microbiology and Infectious Disease antibody
预测分子量46 kDa
翻译后修饰Ubiquitinated in the presence of HIV-1 VIF. Association with VIF targets the protein for proteolysis by the ubiquitin-dependent proteasome pathway.
Phosphorylation at Thr-32 reduces its binding to HIV-1 VIF and subsequent ubiquitination and degradation thus promoting its antiviral activity.
检测图片 (3)
  • ARG64741 anti-APOBEC3G antibody WB image

    Western Blot: Daudi lysate (35µg protein in RIPA buffer) stained with ARG64741 anti-APOBEC3G antibody (0.5µg/ml)

  • ARG64741 anti-APOBEC3G antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human testis tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64741 anti-APOBEC3G antibody at 2.5 µg/ml dilution followed by AP-staining.

  • ARG64741 anti-APOBEC3G antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64741 anti-APOBEC3G antibody at 2.5 µg/ml dilution followed by AP-staining.

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