anti-ARL4A antibody
CAT.NO. : ARG41291
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概述
产品描述 | Rabbit Polyclonal antibody recognizes ARL4A |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, IHC-P |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ARL4A |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 121-200 of Human ARL4A (NP_001032241.1). |
偶联标记 | Un-conjugated |
別名 | ARL4; ADP-ribosylation factor-like protein 4A |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | ARL4A |
全名 | ADP-ribosylation factor-like 4A |
背景介绍 | ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
生物功能 | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. [UniProt] |
细胞定位 | Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is dependent by nucleotide binding. [UniProt] |
预测分子量 | 23 kDa |
翻译后修饰 | Myristoylated. [UniProt] |
检测图片 (2)
ARG41291 anti-ARL4A antibody ICC/IF image
Immunofluorescence: NIH/3T3 cells stained with ARG41291 anti-ARL4A antibody at 1:100 dilution.
ARG41291 anti-ARL4A antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver cancer tissue stained with ARG41291 anti-ARL4A antibody at 1:100 dilution.
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