anti-ASC / TMS1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG43887
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ASC / TMS1 |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ASC / TMS1 |
| 抗原物种 | Mouse |
| 抗原 | Mouse ASC / TMS1 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Apoptosis-associated speck-like protein containing a CARD |
| 別名 | PYCARD; PYD And CARD Domain Containing; CARD5; ASC; Apoptosis-Associated Speck-Like Protein Containing A CARD; TMS-1; Caspase Recruitment Domain-Containing Protein 5; Target Of Methylation-Induced Silencing 1; TMS1; PYD And CARD Domain-Containing Protein; Apoptosis-Associated Speck-Like; HASC; TMS |
应用说明
| 应用建议 |
| ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 基因名称 | PYCARD |
|---|---|
| 全名 | PYD And CARD Domain Containing |
| 背景介绍 | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Modulates host resistance to DNA virus infection, probably by inducing the cleavage of and inactivating CGAS in presence of cytoplasmic double-stranded DNA. |
| 细胞定位 | Cytoplasm, Endoplasmic reticulum, Golgi apparatus, nflammasome, Membrane, Mitochondrion, Nucleus |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (3)
ARG43887 anti-ASC / TMS1 antibody WB image
Western blot: Mouse spleen and Mouse thymus stained with ARG43887 anti-ASC / TMS1 antibody at 0.5 μg/ml.
ARG43887 anti-ASC / TMS1 antibody ICC/IF image
Immunofluorescence: RM1 cells stained with ARG43887 anti-ASC / TMS1 antibody at 5 μg/ml dilution.
ARG43887 anti-ASC / TMS1 antibody FACS image
Flow Cytometry: RAW264.7 cells stained with ARG43887 anti-ASC / TMS1 antibody (blue) at 1 μg/1x10^6 cells dilution.
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