anti-ATP1A3 antibody
CAT.NO. : ARG44999
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概述
产品描述 | Rabbit Polyclonal antibody recognizes ATP1A3 |
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反应物种 | Hu |
应用 | ELISA, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ATP1A3 |
抗原物种 | Human |
抗原 | Synthetic peptide (a.a 444-477) from human ATP1A3. |
偶联标记 | Un-conjugated |
別名 | ATP1A3; ATPase Na+/K+ Transporting Subunit Alpha 3; Sodium/Potassium-Transporting ATPase Subunit Alpha-3; Sodium Pump Subunit Alpha-3; Sodium-Potassium ATPase Catalytic Subunit Alpha-3; ATPase, Na+/K+ Transporting, Alpha 3 Polypeptide; Na(+)/K(+) ATPase Alpha(III) Subunit; Na(+)/K(+) ATPase Alpha-3 Subunit; DYT12; Na+, K+ Activated Adenosine Triphosphatase Alpha Subunit; Sodium/Potassium-Transporting ATPase Alpha-3 Chain; Sodium-Potassium-ATPase, Alpha 3 Polypeptide; Na+/K+ ATPase 3; Dystonia 12; EC 7.2.2.13; EC 3.6.3.9; EC 3.6.3; ATP1A1; CAPOS; DEE99; AHC2; RDP |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A Purified |
缓冲液 | PBS and 0.09% Sodium azide |
抗菌剂 | 0.09% Sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P13637 Human Sodium/potassium-transporting ATPase subunit alpha-3 |
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基因名称 | ATP1A3 |
全名 | ATPase Na+/K+ Transporting Subunit Alpha 3 |
背景介绍 | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
生物功能 | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. [Uniprot] |
细胞定位 | Cell membrane, Membrane. [Uniprot] |
预测分子量 | 112 kDa |
翻译后修饰 | Phosphoprotein. [Uniprot] |
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