anti-BAT3 / BAG6 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes BAT3 / BAG6
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow, Dog, Pig
  • 应用: IHC-P
  • 特异性: This antibody is expected to recognize both reported isoforms (NP_004630.3; NP_542433.1). Reported variants representing identical protein: NP_542434.1, NP_001092004.1, NP_542433.1 (isoform b).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: BAT3 / BAG6
  • Brand:
CAT.NO. : ARG64803
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes BAT3 / BAG6
反应物种Hu
预测物种Ms, Rat, Cow, Dog, Pig
应用IHC-P
特异性This antibody is expected to recognize both reported isoforms (NP_004630.3; NP_542433.1). Reported variants representing identical protein: NP_542434.1, NP_001092004.1, NP_542433.1 (isoform b).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称BAT3 / BAG6
抗原物种Human
抗原C-PETNAPNHPSPAEY
偶联标记Un-conjugated
別名BAG-6; G3; BAG6; Protein G3; BCL2-associated athanogene 6; Protein Scythe; BAT3; HLA-B-associated transcript 3; BAG family molecular chaperone regulator 6; D6S52E; Large proline-rich protein BAG6
应用说明
应用建议
应用推荐稀释比
IHC-P3 - 5 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 7917 Human BAG6

Swiss-port # P46379 Human Large proline-rich protein BAG6

背景介绍This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
研究领域Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody
预测分子量119 kDa
翻译后修饰Ricin can induce a cleavage by the caspase CASP3. The released C-terminal peptide induces apoptosis.
(Microbial infection) In case of infection by L.pneumophila, ubiquitinated by the SCF(LegU1) complex.
检测图片 (1)
  • ARG64803 anti-BAT3 / BAG6 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Spleen. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64803 anti-BAT3 antibody at 3.8 µg/ml dilution followed by AP-staining.

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