anti-CA19-9 antibody [121SLE]
CAT.NO. : ARG63094
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概述
产品描述 | Mouse Monoclonal antibody [121SLE] recognizes CA19-9 |
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反应物种 | Hu |
应用 | ELISA, IHC-P |
特异性 | The clone 121SLE recognizes Sialyl Lewis a containing glycolipids (CA19-9). |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 121SLE |
同位型 | IgM |
靶点名称 | CA19-9 |
抗原 | Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient. |
偶联标记 | Un-conjugated |
別名 | SIAT7F; SIAT7-F; ST6GALNACV; CA19-9 |
应用说明
应用建议 |
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应用说明 | IHC-P: Positive control:colorectal adenocarcinoma Application note:heat mediated antigen retrieval (sodium citrate); mAb incubation 1 hour / RT; detection DAB * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from ascites by precipitation methods and size-exclusion chromatography. |
纯度 | > 95% (by SDS-PAGE) |
缓冲液 | TBS (pH 8.0) and 15 mM Sodium azide |
抗菌剂 | 15 mM Sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | GeneID: 30815 Human ST6GALNAC6 Swiss-port # Q969X2 Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 |
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基因名称 | ST6GALNAC6 |
全名 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 |
背景介绍 | ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008] |
生物功能 | Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)). [UniProt] |
产品亮点 | Related products: CA19-9 antibodies; CA19-9 ELISA Kits; Anti-Mouse IgM secondary antibodies; Related news: More than a biomarker, CA19-9 is a therapeutic target of pancreatic cancer |
研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody |
预测分子量 | 38 kDa |
检测图片 (2)
ARG63094 anti-CA19-9 antibody [121SLE] IHC-P image
Immunohistochemistry: Paraffin-embedded Human pancreas tissue stained with ARG63094 anti-CA19-9 antibody [121SLE] at 10 µg/ml dilution.
ARG63094 anti-Sialyl Lewis a antibody [121SLE] IHC-P image
Immunohistochemistry: Colorectal adenocarcinoma section stained with ARG63094 anti-Sialyl Lewis a antibody [121SLE].
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