anti-CACYBP antibody [3G8]
CAT.NO. : ARG57035
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概述
产品描述 | Mouse Monoclonal antibody [3G8] recognizes CACYBP |
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反应物种 | Hu |
应用 | WB |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 3G8 |
同位型 | IgG2a, kappa |
靶点名称 | CACYBP |
抗原物种 | Human |
抗原 | Recombinant fragment around aa. 1-185 of Human CACYBP. |
偶联标记 | Un-conjugated |
別名 | S100A6-binding protein; SIP; S100A6BP; GIG5; hCacyBP; CacyBP; Siah-interacting protein; Calcyclin-binding protein; PNAS-107 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein A. |
缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 10% Glycerol |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CACYBP |
全名 | calcyclin binding protein |
背景介绍 | The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
生物功能 | May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). [UniProt] |
预测分子量 | 26 kDa |
翻译后修饰 | Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations. |
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