anti-Cathepsin L + Cathepsin V antibody [33/2]
![anti-Cathepsin L + Cathepsin V antibody [33/2]](/upload/image/products/A5649_210_205.png)
![anti-Cathepsin L + Cathepsin V antibody [33/2]](/upload/image/products/A5649.png)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG42684
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [33/2] recognizes Cathepsin L + Cathepsin V |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-Fr, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 33/2 |
| 同位型 | IgG1 |
| 靶点名称 | Cathepsin L + Cathepsin V |
| 抗原物种 | Human |
| 抗原 | Procathepsin L isolated from Human lung cancer cell line EPLC 32M1. |
| 偶联标记 | Un-conjugated |
| 別名 | Cathepsin L: Major excreted protein; CATL; Cathepsin L1; EC 3.4.22.15; CTSL1; MEP Cathepsin V: CTSU; Cathepsin L2; CTSL2; CATL2; Cathepsin U; EC 3.4.22.43 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Unpurified |
| 缓冲液 | Mouse ascites fluid, 1.2% Sodium acetate, 0.01% Sodium azide and 2% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 2% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CTSL; CTSV |
|---|---|
| 全名 | cathepsin L; cathepsin V |
| 背景介绍 | Cathepsin L: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012] Cathepsin V: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011] |
| 生物功能 | Cathepsin L: Important for the overall degradation of proteins in lysosomes. [UniProt] Cathepsin V: Cysteine protease. May have an important role in corneal physiology. [UniProt] |
| 细胞定位 | Cathepsin L and Cathepsin V: Lysosome. [UniProt] |
| 预测分子量 | Cathepsin L: 38 kDa Cathepsin V: 37 kDa |
检测图片 (1)
ARG42684 anti-Cathepsin L + Cathepsin V antibody [33/2] WB image
Western blot: A549 stained with ARG42684 anti-Cathepsin L + Cathepsin V antibody [33/2] at 1 μg/mL dilution.
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