anti-CB1 Receptor antibody
CAT.NO. : ARG63873
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概述
产品描述 | Goat Polyclonal antibody recognizes CB1 Receptor |
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反应物种 | Rat |
预测物种 | Hu, Ms, Dog |
应用 | WB |
特异性 | This antibody is expected to recognise both reported isoforms. Isoform a (NP_057167.2; NP_001153732.1; NP_001153731.1; NP_001153730.1; NP_001153698.1) and isoform b (NP_149421.1). |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CB1 Receptor |
抗原物种 | Human |
抗原 | C-HTSEDGKVQVTRPDQ |
偶联标记 | Un-conjugated |
別名 | CB1K5; CNR; CB1R; Cannabinoid receptor 1; CB-R; CB1; CB1A; CANN6 |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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背景介绍 | This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] |
研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody |
预测分子量 | 53 kDa |
翻译后修饰 | Palmitoylation at Cys-415 is important for recruitment at both plasma membrane and lipid rafts. |
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