anti-CCL21 / Exodus 2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CCL21 / Exodus 2
  • 反应物种: Ms
  • 应用: ELISA, Neut, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CCL21 / Exodus 2
  • 抗原物种: Mouse
  • 抗原: E.coli derived Recombinant Mouse Exodus2.(SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG)
  • Brand:
CAT.NO. : ARG56633
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CCL21 / Exodus 2
反应物种Ms
应用ELISA, Neut, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CCL21 / Exodus 2
抗原物种Mouse
抗原E.coli derived Recombinant Mouse Exodus2.
(SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG)
偶联标记Un-conjugated
別名TCA4; Small-inducible cytokine A21; Beta-chemokine exodus-2; ECL; SCYA21; Secondary lymphoid-tissue chemokine; CKb9; 6Ckine; C-C motif chemokine 21; SLC
应用说明
应用建议
应用推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG56743 as a detection antibody
Neut4.0 - 8.0 µg/ml (To yield [ND50] of the biological activity of mExodus - 2 (100.0 ng/ml) )
WB0.1 - 0.2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称Ccl21c
全名chemokine (C-C motif) ligand 21C (leucine)
背景介绍This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
生物功能Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. [UniProt]
预测分子量15 kDa
检测图片 (3)
  • ARG56633 anti-CCL21 / Exodus 2 antibody WB image

    Western blot: 250 - 0.24 ng of Mouse Exodus-2 stained with ARG56633 anti-CCL21 / Exodus 2 antibody, under reducing conditions.

  • ARG56633 anti-CCL21 / Exodus 2 antibody WB image

    Western blot: 250 - 0.24 ng of Mouse Exodus-2 stained with ARG56633 anti-CCL21 / Exodus 2 antibody, under non-reducing conditions.

  • ARG56633 anti-CCL21 / Exodus 2 antibody standard curve image

    Sandwich ELISA: ARG56633 anti-CCL21 / Exodus 2 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56743 anti-CCL21 / Exodus2 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.

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