anti-CCL8 / MCP2 antibody (Biotin)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes CCL8 / MCP2 |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCL8 / MCP2 |
| 抗原物种 | Mouse |
| 抗原 | E. coli derived recombinant Mouse CCL8 / MCP2. (GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP) |
| 偶联标记 | Biotin |
| 別名 | SCYA10; MCP2; Small-inducible cytokine A8; 6-76; Monocyte chemotactic protein 2; HC14; SCYA8; C-C motif chemokine 8; MCP-2; Monocyte chemoattractant protein 2 |
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
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| 背景介绍 | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014] |
| 生物功能 | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. [UniProt] |
| 预测分子量 | 11 kDa |
| 翻译后修饰 | N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
ARG66048 anti-CCL8 / MCP2 antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Mouse MCP-2 stained with ARG66048 anti-CCL8 / MCP2 antibody (Biotin), under non-reducing conditions.
ARG66048 anti-CCL8 / MCP2 antibody (Biotin) standard curve image
Direct ELISA: ARG66048 anti-CCL8 / MCP2 antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density reading at 405 - 650 nm.
ARG66048 anti-CCL8 / MCP2 antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Mouse MCP-2 stained with ARG66048 anti-CCL8 / MCP2 antibody (Biotin), under reducing conditions.
ARG66048 anti-CCL8 / MCP2 antibody (Biotin) standard curve image
Sandwich ELISA: ARG66048 anti-CCL8 / MCP2 antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG66047 anti-CCL8 / MCP2 antibody as a capture antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
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