anti-CD102 / ICAM2 antibody [3C4]

产品描述: Rat Monoclonal antibody [3C4] recognizes CD102 / ICAM2
反应物种: Ms
应用: BL, FACS, ICC/IF, IHC-Fr, IP
特异性: Mouse CD102. The clone 3C4 reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1.
宿主: Rat
克隆: Monoclonal
克隆号: 3C4
同位型: IgG2a, kappa
靶点名称: CD102 / ICAM2

CAT.NO. : ARG21102

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Size:

100 μg

Product Details

概述

产品描述	Rat Monoclonal antibody [3C4] recognizes CD102 / ICAM2
反应物种	Ms
应用	BL, FACS, ICC/IF, IHC-Fr, IP
特异性	Mouse CD102. The clone 3C4 reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1.
宿主	Rat
克隆	Monoclonal
克隆号	3C4
同位型	IgG2a, kappa
靶点名称	CD102 / ICAM2
抗原物种	Mouse
抗原	COS cells transfected with mouse ICAM-2 cDNA and BW5147 AKR/J mouse thymoma cell line
偶联标记	Un-conjugated
別名	CD102; CD antigen CD102; Intercellular adhesion molecule 2; ICAM-2

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	BBS (pH 8.2)
浓度	0.5 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 15896 Mouse ICAM2 Swiss-port # P35330 Mouse Intercellular adhesion molecule 2
基因名称	ICAM2
全名	intercellular adhesion molecule 2
背景介绍	The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. [UniProt]
预测分子量	31 kDa

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