anti-CD107b / LAMP2 antibody [H4B4] (Biotin)
CAT.NO. : ARG22184
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概述
产品描述 | Biotin-conjugated Mouse Monoclonal antibody [H4B4] recognizes CD107b / LAMP2 |
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反应物种 | Hu, AGMK, R. Mk |
应用 | EM, FACS, ICC/IF, IHC-Fr, IHC-P, Puri, WB |
特异性 | Human/Rhesus/African Green Monkey CD107b |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | H4B4 |
同位型 | IgG1, kappa |
靶点名称 | CD107b / LAMP2 |
抗原物种 | Human |
抗原 | Human adherent peripheral blood cells |
偶联标记 | Biotin |
別名 | CD antigen CD107b; LAMPB; CD107b; LGP110; Lysosome-associated membrane glycoprotein 2; LAMP-2; CD107 antigen-like family member B; Lysosome-associated membrane protein 2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS and 0.1% Sodium azide. |
抗菌剂 | 0.1% Sodium azide |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P13473 Human Lysosome-associated membrane glycoprotein 2 |
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基因名称 | LAMP2 |
全名 | lysosomal-associated membrane protein 2 |
背景介绍 | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008] |
生物功能 | Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. [UniProt] |
预测分子量 | 45 kDa |
翻译后修饰 | O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans. |
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