anti-CD109 antibody [W7C5]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [W7C5] recognizes CD109
  • 反应物种: Hu
  • 应用: FACS
  • 特异性: The mouse monoclonal antibody W7C5 recognizes CD109, an approximately 165 kDa GPI-anchored extracellular protein expressed mainly on various hematopoietic cells, activated T lymphoblasts, activated platelets, and endothelial cells.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: W7C5
  • 同位型: IgG1
  • 靶点名称: CD109
  • Brand:
CAT.NO. : ARG42423
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Product Details
概述
产品描述Mouse Monoclonal antibody [W7C5] recognizes CD109
反应物种Hu
应用FACS
特异性The mouse monoclonal antibody W7C5 recognizes CD109, an approximately 165 kDa GPI-anchored extracellular protein expressed mainly on various hematopoietic cells, activated T lymphoblasts, activated platelets, and endothelial cells.
宿主Mouse
克隆Monoclonal
克隆号W7C5
同位型IgG1
靶点名称CD109
抗原物种Human
抗原WERI-Rb-1 retinoblastoma cell line.
偶联标记Un-conjugated
別名p180; CPAMD7; Platelet-specific Gov antigen; CD109 antigen; r150; 150 kDa TGF-beta-1-binding protein; CD antigen CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7
应用说明
应用建议
应用推荐稀释比
FACS1 - 4 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS and 15 mM Sodium azide.
抗菌剂15 mM Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 135228 Human CD109

Swiss-port # Q6YHK3 Human CD109 antigen

基因名称CD109
全名CD109 molecule
背景介绍This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
生物功能Modulates negatively TGFB1 signaling in keratinocytes. [UniProt]
细胞定位Cell membrane; Lipid-anchor, GPI-anchor. [UniProt]
预测分子量162 kDa
翻译后修饰N-glycosylated.

2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form. [UniProt]
检测图片 (2)
  • ARG42423 anti-CD109 antibody [W7C5] FACS image

    Flow Cytometry: Human peripheral blood stained with ARG42423 anti-CD109 antibody [W7C5] at 1 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.

  • ARG42423 anti-CD109 antibody [W7C5] FACS image

    Flow Cytometry: Separation of Human monocytes (red-filled) from CD109 negative lymphocytes (black-dashed). Human peripheral whole blood stained with ARG42423 anti-CD109 antibody [W7C5] at 1 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.

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