anti-CD123 / IL3RA antibody [6H6] (Biotin)

产品描述: Biotin-conjugated Mouse Monoclonal antibody [6H6] recognizes CD123 / IL3RA
反应物种: Hu
应用: FACS, IHC-Fr, IP, WB
特异性: The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
宿主: Mouse
克隆: Monoclonal
克隆号: 6H6
同位型: IgG1
靶点名称: CD123 / IL3RA

CAT.NO. : ARG42269

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Size:

50 μg

Product Details

概述

产品描述	Biotin-conjugated Mouse Monoclonal antibody [6H6] recognizes CD123 / IL3RA
反应物种	Hu
应用	FACS, IHC-Fr, IP, WB
特异性	The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
宿主	Mouse
克隆	Monoclonal
克隆号	6H6
同位型	IgG1
靶点名称	CD123 / IL3RA
抗原物种	Human
抗原	IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells.
偶联标记	Biotin
別名	IL-3R subunit alpha; CD123; CD antigen CD123; IL3RAY; IL-3R-alpha; IL3RY; IL3RX; IL3R; IL-3RA; IL-3 receptor subunit alpha; hIL-3Ra; Interleukin-3 receptor subunit alpha

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3563 Human IL3RA Swiss-port # P26951 Human Interleukin-3 receptor subunit alpha
基因名称	IL3RA
全名	interleukin 3 receptor, alpha (low affinity)
背景介绍	The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
生物功能	This is a receptor for interleukin-3. [UniProt]
细胞定位	Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	43 kDa

检测图片 (2)

ARG42269 anti-CD123 / IL3RA antibody [6H6] (Biotin) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42269 anti-CD123 / IL3RA antibody [6H6] (Biotin), followed by Streptavidin-PE. Samples were co-stained with anti-HLA DR antibody (APC).
ARG42269 anti-CD123 / IL3RA antibody [6H6] (Biotin) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42269 anti-CD123 / IL3RA antibody [6H6] (Biotin), followed by Streptavidin-APC.

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