anti-CD137 antibody [4B4-1] (low endotoxin)
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Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG65822
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Product Details
概述
| 产品描述 | Azide free and low endotoxin Mouse Monoclonal antibody [4B4-1] recognizes CD137 |
|---|---|
| 反应物种 | Hu |
| 应用 | FuncSt |
| 特异性 | The monoclonal antibody recognizes CD137, an approximately 40 kDa type I transmembrane protein of the TNFR family expressed mainly on activated T cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 4B4-1 |
| 同位型 | IgG1 |
| 靶点名称 | CD137 |
| 抗原物种 | Human |
| 抗原 | Human CD137 |
| 偶联标记 | Un-conjugated |
| 別名 | ILA; CD137; T-cell antigen 4-1BB homolog; CDw137; T-cell antigen ILA; 4-1BB; CD antigen CD137; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 纯化说明 | Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q07011 Human Tumor necrosis factor receptor superfamily member 9 |
|---|---|
| 基因名称 | TNFRSF9 |
| 全名 | tumor necrosis factor receptor superfamily, member 9 |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. [UniProt] |
| 预测分子量 | 28 kDa |
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