anti-CD146 antibody [C264] (FITC)
CAT.NO. : ARG21221
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概述
产品描述 | FITC-conjugated Mouse Monoclonal antibody [C264] recognizes CD146 |
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反应物种 | Chk, Turkey |
应用 | FACS, ICC/IF |
特异性 | Chicken/Turkey MCAM. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | C264 |
同位型 | IgG2b, kappa |
靶点名称 | CD146 |
抗原物种 | Chicken |
抗原 | Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos |
偶联标记 | FITC |
別名 | Cell surface glycoprotein P1H12; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; Cell surface glycoprotein MUC18; Melanoma cell adhesion molecule; CD146; MUC18; CD antigen CD146; S-endo 1 endothelial-associated antigen |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS and 0.1% Sodium azide. |
抗菌剂 | 0.1% Sodium azide |
浓度 | 0.5 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | MCAM |
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全名 | melanoma cell adhesion molecule |
生物功能 | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. [UniProt] |
预测分子量 | 72 kDa |
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