anti-CD150 / SLAM antibody [9D1]

Key features and details

  • 产品描述: Rat Monoclonal antibody [9D1] recognizes CD150 / SLAM.This product recognizes murine CD150, also known as signalling lymphocyte activation molecule (SLAM). Murine CD150 is a 75 kDa cell surface glycoprotein that is expressed on T-cells and B-cells, and is upregulated on activated T-cells and stimulated macrophages. The extracellular domain of CD150 is the receptor for the measles virus (Erlenhoefer et al. 2001) and acts as a co-activator on T-cells and B-cells.Rat anti Mouse CD150 antibody, clone 9D1 has functional activity (Howie et al. 2002).
  • 反应物种: Ms
  • 应用: FACS
  • 宿主: Rat
  • 克隆: Monoclonal
  • 克隆号: 9D1
  • 同位型: IgG1
  • 靶点名称: CD150 / SLAM
  • 抗原物种: Mouse
  • Brand:
CAT.NO. : ARG23612
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Product Details
概述
产品描述Rat Monoclonal antibody [9D1] recognizes CD150 / SLAM.
This product recognizes murine CD150, also known as signalling lymphocyte activation molecule (SLAM). Murine CD150 is a 75 kDa cell surface glycoprotein that is expressed on T-cells and B-cells, and is upregulated on activated T-cells and stimulated macrophages. The extracellular domain of CD150 is the receptor for the measles virus (Erlenhoefer et al. 2001) and acts as a co-activator on T-cells and B-cells.Rat anti Mouse CD150 antibody, clone 9D1 has functional activity (Howie et al. 2002).
反应物种Ms
应用FACS
宿主Rat
克隆Monoclonal
克隆号9D1
同位型IgG1
靶点名称CD150 / SLAM
抗原物种Mouse
抗原CHO cells stably transfected with Mouse CD150.
偶联标记Un-conjugated
別名Signaling lymphocytic activation molecule; IPO-3; CD150; SLAM; CDw150; CD antigen CD150
应用说明
应用建议
应用推荐稀释比
FACS1:25 - 1:100
应用说明FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS and 0.09% Sodium azide.
抗菌剂0.09% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 27218 Mouse SLAMF1

Swiss-port # Q9QUM4 Mouse Signaling lymphocytic activation molecule

基因名称SLAMF1
全名signaling lymphocytic activation molecule family member 1
生物功能High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. [UniProt]
预测分子量37 kDa
翻译后修饰Phosphorylated on tyrosine residues by FYN. [UniProt]
检测图片 (2)
  • ARG23612 anti-CD150 / SLAM antibody [9D1] FACS image

    Flow Cytometry: Mouse thymus cells stained with ARG23612 anti-CD150 / SLAM antibody [9D1].

  • ARG23612 anti-CD150 / SLAM antibody [9D1] FACS image

    Flow Cytometry: Mouse thymus cells stained with ARG23612 anti-CD150 / SLAM antibody [9D1].

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