anti-CD150 / SLAM antibody [9D1] (low endotoxin)
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Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG23611
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Product Details
概述
| 产品描述 | Azide free and low endotoxin Rat Monoclonal antibody [9D1] recognizes CD150 / SLAM. This product recognizes murine CD150, also known as signalling lymphocyte activation molecule (SLAM) . Murine CD150 is a 75 kDa cell surface glycoprotein that is expressed on T-cells and B-cells, and is upregulated on activated T-cells and stimulated macrophages. The extracellular domain of CD150 is the receptor for the measles virus (Erlenhoefer et al. 2001) and acts as a co-activator on T-cells and B-cells.Rat anti Mouse CD150 antibody, clone 9D1 has functional activity (Howie et al. 2002). |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS, FuncSt |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 9D1 |
| 同位型 | IgG1 |
| 靶点名称 | CD150 / SLAM |
| 抗原物种 | Mouse |
| 抗原 | CHO cells stably transfected with Mouse CD150. |
| 偶联标记 | Un-conjugated |
| 別名 | Signaling lymphocytic activation molecule; IPO-3; CD150; SLAM; CDw150; CD antigen CD150 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 纯化说明 | Low endotoxin |
| 缓冲液 | PBS. |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9QUM4 Mouse Signaling lymphocytic activation molecule |
|---|---|
| 基因名称 | SLAMF1 |
| 全名 | signaling lymphocytic activation molecule family member 1 |
| 生物功能 | High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. [UniProt] |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues by FYN. [UniProt] |
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