anti-CD157 / BST1 antibody [SY11B5] (APC)
CAT.NO. : ARG42318
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概述
产品描述 | APC-conjugated Mouse Monoclonal antibody [SY11B5] recognizes CD157 / BST1 |
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反应物种 | Hu, NHuPrm |
应用 | FACS |
特异性 | The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPI-anchored extracellular protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | SY11B5 |
同位型 | IgG1, kappa |
靶点名称 | CD157 / BST1 |
抗原物种 | Human |
抗原 | Human CD157. |
偶联标记 | APC |
別名 | cADPr hydrolase 2; ADP-ribosyl cyclase 2; Cyclic ADP-ribose hydrolase 2; BST-1; Bone marrow stromal antigen 1; CD157; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; CD antigen CD157; EC 3.2.2.6 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified |
缓冲液 | PBS and 15 mM Sodium azide. |
抗菌剂 | 15 mM Sodium azide |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q10588 Human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
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基因名称 | BST1 |
全名 | bone marrow stromal cell antigen 1 |
背景介绍 | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
生物功能 | Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. [UniProt] |
细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
预测分子量 | 36 kDa |
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