anti-CD20 antibody [B-Ly1], F(ab')2 fragment (PE)

Key features and details

  • 产品描述: PE-conjugated F(ab'2) fragment of Mouse Monoclonal antibody [B-Ly1] recognizes CD20
  • 反应物种: Hu
  • 应用: BL, FACS, IHC-Fr, IHC-P
  • 特异性: Human CD20
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: B-Ly1
  • 同位型: F(ab')2 IgG1, kappa
  • 靶点名称: CD20
  • Brand:
CAT.NO. : ARG21283
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Product Details
概述
产品描述PE-conjugated F(ab'2) fragment of Mouse Monoclonal antibody [B-Ly1] recognizes CD20
反应物种Hu
应用BL, FACS, IHC-Fr, IHC-P
特异性Human CD20
宿主Mouse
克隆Monoclonal
克隆号B-Ly1
同位型F(ab')2 IgG1, kappa
靶点名称CD20
抗原物种Human
偶联标记PE
別名Bp35; LEU-16; B-lymphocyte surface antigen B1; B-lymphocyte antigen CD20; CD20; S7; CD antigen CD20; Leukocyte surface antigen Leu-16; B1; CVID5; Membrane-spanning 4-domains subfamily A member 1; MS4A2
应用说明
应用建议
应用推荐稀释比
BLAssay-dependent
FACS10 µl/10^6 cells
IHC-FrAssay-dependent
IHC-PAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液PBS, 0.1% Sodium azide and Sucrose.
抗菌剂0.1% Sodium azide
稳定剂Sucrose
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 931 Human MS4A1

Swiss-port # P11836 Human B-lymphocyte antigen CD20

基因名称MS4A1
全名membrane-spanning 4-domains, subfamily A, member 1
背景介绍CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
生物功能CD20 is a B-lymphocyte-specific membrane protein. It plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:7684739, PubMed:12920111, PubMed:18474602). [UniProt]
产品亮点Related products:
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预测分子量33 kDa
翻译后修饰Phosphorylated. Might be functionally regulated by protein kinase(s).
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