anti-CD20 antibody [B-Ly1] (PE-Cyanine 5)
CAT.NO. : ARG21278
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概述
产品描述 | PE-Cyanine 5-conjugated Mouse Monoclonal antibody [B-Ly1] recognizes CD20 |
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反应物种 | Hu |
应用 | BL, FACS, IHC-Fr, IHC-P |
特异性 | Human CD20 |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | B-Ly1 |
同位型 | IgG1, kappa |
靶点名称 | CD20 |
抗原物种 | Human |
偶联标记 | PE-Cyanine 5 |
別名 | Bp35; LEU-16; B-lymphocyte surface antigen B1; B-lymphocyte antigen CD20; CD20; S7; CD antigen CD20; Leukocyte surface antigen Leu-16; B1; CVID5; Membrane-spanning 4-domains subfamily A member 1; MS4A2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
抗菌剂 | 0.1% Sodium azide |
稳定剂 | Sucrose |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | MS4A1 |
全名 | membrane-spanning 4-domains, subfamily A, member 1 |
背景介绍 | CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008] |
生物功能 | CD20 is a B-lymphocyte-specific membrane protein. It plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:7684739, PubMed:12920111, PubMed:18474602). [UniProt] |
产品亮点 | Related products: CD20 antibodies; CD20 ELISA Kits; CD20 Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: New antibody panels and duos for Tumor immune microenvironment Tumor-Infiltrating Lymphocytes (TILs) Exploring Antiviral Immune Response |
研究领域 | Cancer antibody; Developmental Biology antibody; Immune System antibody; B cell Marker antibody; Immature B Cell Marker antibody; Inflammatory Cell Marker antibody; Tumor-infiltrating Lymphocyte Study antibody |
预测分子量 | 33 kDa |
翻译后修饰 | Phosphorylated. Might be functionally regulated by protein kinase(s). |
检测图片 (2)
ARG21278 anti-CD20 antibody [B-Ly1] (PE-Cyanine 5) FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG21278 anti-CD20 antibody [B-Ly1] (PE-Cyanine 5) and ARG21260 anti-CD19 antibody [SJ25-C1] (PE).
ARG21278 anti-CD20 antibody [B-Ly1] (PE-Cyanine 5) FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG21278 anti-CD20 antibody [B-Ly1] (PE-Cyanine 5).
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