anti-CD200R antibody [OX108] (PE)
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![anti-CD200R antibody [OX108] (PE)](/upload/image/products/ARG22998_FACS_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG22998
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Product Details
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [OX108] recognizes CD200R Mouse anti Human CD200R antibody, clone OX108 recognizes human CD200R, a cell surface glycoprotein (also known as OX2R). In humans CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells, CD200-CD200R interaction may be involved in the control of myeloid cellular function (Wright et al. 2003). Levels of expression on resting perispheral blood cells are relatively low. |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | OX108 |
| 同位型 | IgG1 |
| 靶点名称 | CD200R |
| 抗原物种 | Human |
| 抗原 | Fusion protein hCD200RCD4d3+4. |
| 偶联标记 | PE |
| 別名 | MOX2R; Cell surface glycoprotein CD200 receptor 1; CD200R; Cell surface glycoprotein OX2 receptor 1; OX2R; HCRTR2; CD200 cell surface glycoprotein receptor |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA and 5% Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8TD46 Human Cell surface glycoprotein CD200 receptor 1 |
|---|---|
| 基因名称 | CD200R1 |
| 全名 | CD200 receptor 1 |
| 背景介绍 | This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| 生物功能 | Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. [UniProt] |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform. |
检测图片 (1)
ARG22998 anti-CD200R antibody [OX108] (PE) FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG22998 anti-CD200R antibody [OX108] (PE).
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