anti-CD21 antibody [LT21] (PerCP)
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Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG42361
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Product Details
概述
| 产品描述 | PerCP-conjugated Mouse Monoclonal antibody [LT21] recognizes CD21 |
|---|---|
| 反应物种 | Hu, Cow, Dog, Pig |
| 应用 | FACS |
| 特异性 | The antibody LT21 reacts with an extracellular epitope of CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | LT21 |
| 同位型 | IgG1 |
| 靶点名称 | CD21 |
| 抗原物种 | Human |
| 抗原 | IM9 Human B-lymphoblastoid cell line. |
| 偶联标记 | PerCP |
| 別名 | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CR2 |
| 全名 | complement component (3d/Epstein Barr virus) receptor 2 |
| 背景介绍 | This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| 生物功能 | Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047). (Microbial infection) Acts as a receptor for Epstein-Barr virus. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 113 kDa |
检测图片 (2)
ARG42361 anti-CD21 antibody [LT21] (PerCP) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG42361 anti-CD21 antibody [LT21] (PerCP) at 10 µl / 100 µl of peripheral whole blood.
ARG42361 anti-CD21 antibody [LT21] (PerCP) FACS image
Flow Cytometry: Separation of Human CD21 lymphocytes (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG42361 anti-CD21 antibody [LT21] (PerCP) at 10 µl / 100 µl of peripheral whole blood.
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