anti-CD23 antibody [2G8] (APC)

Key features and details

  • 产品描述: APC-conjugated Rat Monoclonal antibody [2G8] recognizes CD23
  • 反应物种: Ms
  • 应用: FACS, IHC-Fr
  • 特异性: Mouse CD23.
  • 宿主: Rat
  • 克隆: Monoclonal
  • 克隆号: 2G8
  • 同位型: IgG2a, kappa
  • 靶点名称: CD23
  • Brand:
CAT.NO. : ARG20877
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Product Details
概述
产品描述APC-conjugated Rat Monoclonal antibody [2G8] recognizes CD23
反应物种Ms
应用FACS, IHC-Fr
特异性Mouse CD23.
宿主Rat
克隆Monoclonal
克隆号2G8
同位型IgG2a, kappa
靶点名称CD23
抗原物种Mouse
抗原FcεR isolated from B cell lymphoma cell line M12.4.5
偶联标记APC
別名CD23A; BLAST-2; Lymphocyte IgE receptor; CLEC4J; Immunoglobulin E-binding factor; CD23; IGEBF; Fc-epsilon-RII; CD antigen CD23; FCE2; Low affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4 member J
应用说明
应用建议
应用推荐稀释比
FACS
IHC-FrAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液PBS, 0.1% Sodium azide and Sucrose.
抗菌剂0.1% Sodium azide
稳定剂Sucrose
浓度0.1 mg/ml
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称FCER2
全名Fc receptor, IgE, low affinity II, alpha polypeptide
背景介绍The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
生物功能Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [UniProt]
预测分子量36 kDa
翻译后修饰N- and O-glycosylated.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
检测图片 (1)
  • ARG20877 anti-CD23 antibody [2G8] (APC) FACS image

    Flow Cytometry: BALB/c Mouse splenocytes stained with ARG20877 anti-CD23 antibody [2G8] (APC) and ARG20817 anti-CD3e antibody [C363.29B] (FITC).

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