anti-CD23 antibody [2G8] (FITC)
CAT.NO. : ARG20874
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概述
产品描述 | FITC-conjugated Rat Monoclonal antibody [2G8] recognizes CD23 |
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反应物种 | Ms |
应用 | FACS, IHC-Fr |
特异性 | Mouse CD23. |
宿主 | Rat |
克隆 | Monoclonal |
克隆号 | 2G8 |
同位型 | IgG2a, kappa |
靶点名称 | CD23 |
抗原物种 | Mouse |
抗原 | FcεR isolated from B cell lymphoma cell line M12.4.5 |
偶联标记 | FITC |
別名 | CD23A; BLAST-2; Lymphocyte IgE receptor; CLEC4J; Immunoglobulin E-binding factor; CD23; IGEBF; Fc-epsilon-RII; CD antigen CD23; FCE2; Low affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4 member J |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS and 0.1% Sodium azide. |
抗菌剂 | 0.1% Sodium azide |
浓度 | 0.5 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | FCER2 |
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全名 | Fc receptor, IgE, low affinity II, alpha polypeptide |
背景介绍 | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
生物功能 | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [UniProt] |
预测分子量 | 36 kDa |
翻译后修饰 | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. |
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