anti-CD25 antibody [7D4]

产品描述: Rat Monoclonal antibody [7D4] recognizes CD25
反应物种: Ms
应用: BL, Depletion, FACS, IHC-Fr, IP, Neut
特异性: Mouse CD25. The clone 7D4 reacts with an epitope between amino acids 125 and 212 that is distinct from that recognized by The clone 3C7. While The clone 7D4 does not block the binding of IL-2 to CD25, when used in combination with The clone 3C7 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone.
宿主: Rat
克隆: Monoclonal
克隆号: 7D4
同位型: IgM, kappa
靶点名称: CD25

CAT.NO. : ARG20879

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Size:

250 μg

Product Details

概述

产品描述	Rat Monoclonal antibody [7D4] recognizes CD25
反应物种	Ms
应用	BL, Depletion, FACS, IHC-Fr, IP, Neut
特异性	Mouse CD25. The clone 7D4 reacts with an epitope between amino acids 125 and 212 that is distinct from that recognized by The clone 3C7. While The clone 7D4 does not block the binding of IL-2 to CD25, when used in combination with The clone 3C7 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone.
宿主	Rat
克隆	Monoclonal
克隆号	7D4
同位型	IgM, kappa
靶点名称	CD25
抗原物种	Mouse
抗原	IL-2 dependent BALB/c helper T cell clone HT2
偶联标记	Un-conjugated
別名	IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	BBS (pH 8.2)
浓度	0.5 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 16184 Mouse IL2RA Swiss-port # P01590 Mouse Interleukin-2 receptor subunit alpha
基因名称	IL2RA
全名	interleukin 2 receptor, alpha chain
背景介绍	The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
生物功能	Receptor for interleukin-2. [UniProt]
研究领域	Immune System antibody; Pre-B Cell Marker antibody
预测分子量	31 kDa

检测图片 (1)

ARG20879 anti-CD25 antibody [7D4] FACS image
Flow Cytometry: Con-A stimulated BALB/c Mouse splenocytes stained with ARG20879 anti-CD25 antibody [7D4] followed by ARG23835 Mouse anti-Rat IgM antibody [M2A1] (FITC).

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