anti-CD25 antibody [PC61.5.3] (FITC)
CAT.NO. : ARG23413
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概述
产品描述 | FITC-conjugated Rat Monoclonal antibody [PC61.5.3] recognizes CD25 Rat anti Mouse CD25 antibody, clone PC61.5.3 reacts with the low affinity alpha chain of the interleukin-2 receptor present on activated T and B cells in mice. Rat anti Mouse CD25 antibody, clone PC61.5.3 is reported to inhibit IL-2 binding and IL-2 dependent proliferation. |
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反应物种 | Ms |
应用 | FACS |
宿主 | Rat |
克隆 | Monoclonal |
克隆号 | PC61.5.3 |
同位型 | IgG1 |
靶点名称 | CD25 |
抗原物种 | Mouse |
抗原 | B6.1 CTL cell line. |
偶联标记 | FITC |
別名 | IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10 |
应用说明
应用建议 |
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应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS, 0.09% Sodium azide and 1% BSA. |
抗菌剂 | 0.09% Sodium azide |
稳定剂 | 1% BSA |
浓度 | 0.1 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P01590 Mouse Interleukin-2 receptor subunit alpha |
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基因名称 | IL2RA |
全名 | interleukin 2 receptor, alpha |
背景介绍 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009] |
生物功能 | Receptor for interleukin-2. [UniProt] |
研究领域 | Immune System antibody; Pre-B Cell Marker antibody |
预测分子量 | 31 kDa |
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