anti-CD258 / LIGHT antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes CD258 / LIGHT |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD258 / LIGHT |
| 抗原物种 | Human |
| 抗原 | Hi-5 Insect cells derived Recombinant Human LIGHT. (RLGEMVTRLP DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV) |
| 偶联标记 | Un-conjugated |
| 別名 | CD258; Herpes virus entry mediator ligand; HVEML; HVEM-L; Herpesvirus entry mediator ligand; LTg; LIGHT; CD antigen CD258; TR2; Tumor necrosis factor ligand superfamily member 14 |
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # O43557 Human Tumor necrosis factor ligand superfamily member 14 |
|---|---|
| 基因名称 | TNFSF14 |
| 全名 | tumor necrosis factor (ligand) superfamily, member 14 |
| 背景介绍 | The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. [UniProt] |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | N-glycosylated. The soluble form of isoform 1 derives from the membrane form by proteolytic processing. |
ARG56832 anti-CD258 / LIGHT antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded sections of Human normal placenta. The recommended ARG56832 anti-CD258 / LIGHT antibody concentration is 2.5 µg/ml with an overnight incubation at 4˚C. An HRP-labeled polymer detection system was used with a DAB chromogen. Antigen Retrieval: Boil tissue section in a buffer (pH 8.0) followed by cooling at RT for 20 min.
ARG56832 anti-CD258 / LIGHT antibody WB image
Western blot: 250 - 0.24 ng of Human LIGHT stained with ARG56832 anti-CD258 / LIGHT antibody, under reducing conditions.
ARG56832 anti-CD258 / LIGHT antibody standard curve image
Sandwich ELISA: ARG56832 anti-CD258 / LIGHT antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with Biotinylated anti-LIGHT antibody as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
ARG56832 anti-CD258 / LIGHT antibody WB image
Western blot: 250 - 0.24 ng of Human LIGHT stained with ARG56832 anti-CD258 / LIGHT antibody, under non-reducing conditions.
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