anti-CD3 antibody [KT3] (APC)
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Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG23047
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Product Details
概述
| 产品描述 | APC-conjugated Rat Monoclonal antibody [KT3] recognizes CD3 CD3 antibody, clone KT3 recognizes the mouse CD3 antigen expressed by mature T cells. Clone KT3 may be used to trigger proliferation and cytotoxicity of CD3 positive cells. |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS, IHC-Fr |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | KT3 |
| 同位型 | IgG2a |
| 靶点名称 | CD3 |
| 抗原物种 | Mouse |
| 抗原 | CBAT6 thymocytes. |
| 偶联标记 | APC |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-Fr: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Arigo recommends the use of acetone fixation for frozen sections. FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA and 5% Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CD3D, CD3E, CD3G, CD247 |
|---|---|
| 全名 | CD3 Delta Subunit Of T-Cell Receptor Complex, CD3 Epsilon Subunit Of T-Cell Receptor Complex, CD3 Gamma Subunit Of T-Cell Receptor Complex, CD247 Molecule |
| 背景介绍 | CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex. |
| 产品亮点 | Related products: CD3 antibodies; CD3 ELISA Kits; CD3 Duos / Panels; CD3 recombinant proteins; Anti-Rat IgG secondary antibodies; Related news: New antibody panels and duos for Tumor immune microenvironment Tumor-Infiltrating Lymphocytes (TILs) Exploring Antiviral Immune Response |
| 预测分子量 | 20 kDa |
检测图片 (2)
ARG23047 anti-CD3 antibody [KT3] (APC) FACS image
Flow Cytometry: Figure A. Alexa Fluor 488 conjugated rat anti mouse CD8a and APC conjugated rat IgG2a isotyoe control. Figure B. Alexa Fluor 488 conjugated rat anti mouse CD8a and ARG23047 anti-CD3 antibody [KT3] (APC). All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells.
ARG23047 anti-CD3 antibody [KT3] (APC) FACS image
Flow Cytometry: Figure A. RPE conjugated Rat anti Mouse CD4 and APC conjugated Rat IgG2a isotype control. Figure B. RPE conjugated Rat anti Mouse CD4 and ARG23047 anti-CD3 antibody [KT3] (APC). All experiments performed on murine splenocytes.
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