anti-CD30 antibody [mCD30.1] (FITC)
CAT.NO. : ARG22014
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概述
产品描述 | FITC-conjugated Hamster Monoclonal antibody [mCD30.1] recognizes CD30 |
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反应物种 | Ms |
应用 | BL, FACS |
特异性 | Mouse CD30 |
宿主 | Hamster |
克隆 | Monoclonal |
克隆号 | mCD30.1 |
同位型 | IgG1 |
靶点名称 | CD30 |
抗原物种 | Mouse |
抗原 | Mouse CD30-Mouse IgG1 fusion protein |
偶联标记 | FITC |
別名 | Tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30; Ki-1; Lymphocyte activation antigen CD30; CD antigen CD30; D1S166E; CD30L receptor |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS and 0.1% Sodium azide. |
抗菌剂 | 0.1% Sodium azide |
浓度 | 0.5 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q60846 Mouse Tumor necrosis factor receptor superfamily member 8 |
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基因名称 | TNFRSF8 |
全名 | tumor necrosis factor receptor superfamily, member 8 |
背景介绍 | CD30 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
生物功能 | CD30 is a receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898). [UniProt] |
预测分子量 | 64 kDa |
翻译后修饰 | Phosphorylated on serine and tyrosine residues. |
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