anti-CD48 antibody [B333 (5-4.8)]
CAT.NO. : ARG62419
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概述
产品描述 | Mouse Monoclonal antibody [B333 (5-4.8)] recognizes CD48 |
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反应物种 | Hu |
应用 | FACS, ICC/IF, IHC-Fr, WB |
特异性 | Reacts with CD48, a 45 kD glycosylphosphatidylinositol linked cell surface molecules. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | B333 (5-4.8) |
同位型 | IgG2a |
靶点名称 | CD48 |
抗原物种 | Human |
抗原 | Human PBL cell line |
偶联标记 | Un-conjugated |
別名 | Leukocyte antigen MEM-102; B-lymphocyte activation marker BLAST-1; CD48 antigen; BCM1 surface antigen; CD antigen CD48; TCT.1; BLAST1; BCM1; MEM-102; mCD48; Signaling lymphocytic activation molecule 2; BLAST; hCD48; SLAMF2; SLAM family member 2 |
应用说明
应用说明 | FACS: 1-5µg for 106 cells. ICC/IF: 5 - 20 µg/ml. IHC-Fr: 5 - 20 µg/ml. WB: 1 - 5 µg/ml. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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阳性对照 | Human Tonsil and Lymph Node |
属性
形式 | Liquid |
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纯化 | Protein G purified |
缓冲液 | PBS (pH 8.0) and 0.05% Sodium azide |
抗菌剂 | 0.05% Sodium azide |
浓度 | 0.2 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CD48 |
全名 | CD48 molecule |
背景介绍 | This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
生物功能 | Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. [UniProt] |
研究领域 | Immune System antibody |
预测分子量 | 28 kDa |
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