anti-CD52 antibody [YTH34.5] (FITC)
![anti-CD52 antibody [YTH34.5] (FITC)](/upload/image/products/ARG22825_FACS_1_210_205.jpg)
![anti-CD52 antibody [YTH34.5] (FITC)](/upload/image/products/ARG22825_FACS_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG22825
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Product Details
概述
| 产品描述 | FITC-conjugated Rat Monoclonal antibody [YTH34.5] recognizes CD52 Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link (Xia et al. 1991). The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kDa, considerably reduced following N-glycanase treatment (Rowan et al. 1998).CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.Humanised versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies (Dearden et al. 2002; Pettitt et al. 2012). |
|---|---|
| 反应物种 | Hu, R. Mk |
| 应用 | FACS |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | YTH34.5 |
| 同位型 | IgG2b |
| 靶点名称 | CD52 |
| 抗原物种 | Human |
| 抗原 | Human lymphocytes. |
| 偶联标记 | FITC |
| 別名 | He5; CAMPATH-1 antigen; Human epididymis-specific protein 5; Cambridge pathology 1 antigen; CDw52; Epididymal secretory protein E5; CDW52; CD antigen CD52 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | FACS: use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.09% Sodium azide and 1% BSA |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD52 |
| 全名 | CD52 molecule |
| 生物功能 | May play a role in carrying and orienting carbohydrate, as well as having a more specific role. [UniProt] |
| 预测分子量 | 7 kDa |
检测图片 (1)
ARG22825 anti-CD52 antibody [YTH34.5] (FITC) FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG22825 anti-CD52 antibody [YTH34.5] (FITC).
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