anti-CD54 / ICAM1 antibody [YN1/1.7.4] (APC)
CAT.NO. : ARG20940
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概述
产品描述 | APC-conjugated Rat Monoclonal antibody [YN1/1.7.4] recognizes CD54 / ICAM1 |
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反应物种 | Ms |
应用 | BL, FACS, ICC/IF, IHC-Fr, WB |
特异性 | Mouse CD54. |
宿主 | Rat |
克隆 | Monoclonal |
克隆号 | YN1/1.7.4 |
同位型 | IgG2b, kappa |
靶点名称 | CD54 / ICAM1 |
抗原物种 | Mouse |
抗原 | Mouse NS-1 cells |
偶联标记 | APC |
別名 | CD54; CD antigen CD54; BB2; P3.58; Intercellular adhesion molecule 1; Major group rhinovirus receptor; ICAM-1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
抗菌剂 | 0.1% Sodium azide |
稳定剂 | Sucrose |
浓度 | 0.1 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | Icam1 |
全名 | intercellular adhesion molecule 1 |
背景介绍 | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008] |
生物功能 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody |
预测分子量 | 58 kDa |
翻译后修饰 | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
检测图片 (2)
ARG20940 anti-CD54 / ICAM1 antibody [YN1/1.7.4] (APC) FACS image
Flow Cytometry: C57BL/6 Mouse splenocytes stained with ARG20940 anti-CD54 / ICAM1 antibody [YN1/1.7.4] (APC).
ARG20940 anti-CD54 / ICAM1 antibody [YN1/1.7.4] (APC) FACS image
Flow Cytometry: C57BL/6 Mouse splenocytes stained with ARG20940 anti-CD54 / ICAM1 antibody [YN1/1.7.4] (APC) and ARG22072 anti-NK1.1 / CD161bc antibody [PK136] (FITC).
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