anti-CD54 / ICAM1 antibody [YN1/1.7.4] (low endotoxin)

Key features and details

  • 产品描述: Azide free and low endotoxin Rat Monoclonal antibody [YN1/1.7.4] recognizes CD54 / ICAM1
  • 反应物种: Ms
  • 应用: BL, FACS, ICC/IF, IHC-Fr, IP, Puri, WB
  • 特异性: Mouse CD54.
  • 宿主: Rat
  • 克隆: Monoclonal
  • 克隆号: YN1/1.7.4
  • 同位型: IgG2b, kappa
  • 靶点名称: CD54 / ICAM1
  • Brand:
CAT.NO. : ARG20941
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Product Details
概述
产品描述Azide free and low endotoxin Rat Monoclonal antibody [YN1/1.7.4] recognizes CD54 / ICAM1
反应物种Ms
应用BL, FACS, ICC/IF, IHC-Fr, IP, Puri, WB
特异性Mouse CD54.
宿主Rat
克隆Monoclonal
克隆号YN1/1.7.4
同位型IgG2b, kappa
靶点名称CD54 / ICAM1
抗原物种Mouse
抗原Mouse NS-1 cells
偶联标记Un-conjugated
別名CD54; CD antigen CD54; BB2; P3.58; Intercellular adhesion molecule 1; Major group rhinovirus receptor; ICAM-1
应用说明
应用建议
应用推荐稀释比
BLAssay-dependent
FACSAssay-dependent
ICC/IFAssay-dependent
IHC-FrAssay-dependent
IPAssay-dependent
PuriAssay-dependent
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明Low endotoxin
缓冲液PBS
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15894 Mouse ICAM1

Swiss-port # P13597 Mouse Intercellular adhesion molecule 1

基因名称Icam1
全名intercellular adhesion molecule 1
背景介绍This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
生物功能ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). [UniProt]
研究领域Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody
预测分子量58 kDa
翻译后修饰Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
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