anti-CD56 / NCAM antibody [MEM-188] (FITC)

Key features and details

  • 产品描述: FITC-conjugated Mouse Monoclonal antibody [MEM-188] recognizes CD56 / NCAM
  • 反应物种: Hu, NHuPrm
  • 应用: FACS
  • 特异性: The clone MEM-188 reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested. HLDA VI; WS code A055HLDA VI; WS Code NK26HLDA VII; WS code 70077
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: MEM-188
  • 同位型: IgG2a
  • 靶点名称: CD56 / NCAM
  • Brand:
CAT.NO. : ARG62895
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Product Details
概述
产品描述FITC-conjugated Mouse Monoclonal antibody [MEM-188] recognizes CD56 / NCAM
反应物种Hu, NHuPrm
应用FACS
特异性The clone MEM-188 reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
HLDA VI; WS code A055
HLDA VI; WS Code NK26
HLDA VII; WS code 70077
宿主Mouse
克隆Monoclonal
克隆号MEM-188
同位型IgG2a
靶点名称CD56 / NCAM
抗原物种Human
抗原KG-1 human acute myelogenous leukemia cell line
偶联标记FITC
別名CD56; NCAM; CD antigen CD56; N-CAM-1; MSK39; NCAM-1; Neural cell adhesion molecule 1
应用说明
应用建议
应用推荐稀释比
FACS20 µl / 10^6 cells
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
缓冲液PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂15 mM Sodium azide
稳定剂0.2% (w/v) high-grade protease free BSA
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4684 Human NCAM1

Swiss-port # P13591 Human Neural cell adhesion molecule 1

基因名称NCAM1
全名neural cell adhesion molecule 1
背景介绍CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
生物功能This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. [UniProt]
产品亮点Related products:
CD56 antibodies; CD56 ELISA Kits; CD56 Duos / Panels; Anti-Mouse IgG secondary antibodies;
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研究领域Developmental Biology antibody; Neuroscience antibody; General Lymphocyte Marker Study antibody; Natural killer cells antibody
预测分子量95 kDa
检测图片 (1)
  • ARG62895 anti-CD56 / NCAM antibody [MEM-188] (FITC) FACS image

    Flow Cytometry: Human peripheral blood cells stained with ARG62895 anti-CD56 / NCAM antibody [MEM-188] (FITC).

参考文献

克隆号文献

Fluorescent protein-expressing neural progenitor cells as a tool for transplantation studies.

FACS / Mouse

Skardelly M et al.
PLoS One.,  (2014)

publication_link

 

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