anti-CD57 antibody [NK-1] (Biotin)

Key features and details

  • 产品描述: Biotin-conjugated Mouse Monoclonal antibody [NK-1] recognizes CD57
  • 反应物种: Hu
  • 应用: BL, FACS, ICC/IF, IHC-Fr, IHC-P, Puri, WB
  • 特异性: Human CD57.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: NK-1
  • 同位型: IgM, kappa
  • 靶点名称: CD57
  • Brand:
CAT.NO. : ARG21391
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Product Details
概述
产品描述Biotin-conjugated Mouse Monoclonal antibody [NK-1] recognizes CD57
反应物种Hu
应用BL, FACS, ICC/IF, IHC-Fr, IHC-P, Puri, WB
特异性Human CD57.
宿主Mouse
克隆Monoclonal
克隆号NK-1
同位型IgM, kappa
靶点名称CD57
抗原物种Human
抗原Membrane extract of the human lymphoblastoid cell line HSB-2
偶联标记Biotin
別名Glucuronosyltransferase P; CD57; LEU7; GlcAT-P; GLCATP; HNK1; GlcUAT-P; NK1; Beta-1,3-glucuronyltransferase 1; EC 2.4.1.135; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; GLCUATP; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; NK-1
应用说明
应用建议
应用推荐稀释比
BLAssay-dependent
FACS10 µl/10^6 cells
ICC/IFAssay-dependent
IHC-FrAssay-dependent
IHC-PAssay-dependent
PuriAssay-dependent
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液PBS and 0.1% Sodium azide.
抗菌剂0.1% Sodium azide
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 27087 Human B3GAT1

Swiss-port # Q9P2W7 Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

基因名称B3GAT1
全名beta-1,3-glucuronyltransferase 1
背景介绍The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
生物功能Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity). [UniProt]
预测分子量38 kDa
翻译后修饰The soluble form derives from the membrane form by proteolytic processing.
检测图片 (1)
  • ARG21391 anti-CD57 antibody [NK-1] (Biotin) FACS image

    Flow Cytometry: Human peripheral blood lymphocytes stained with ARG21391 anti-CD57 antibody [NK-1] (Biotin) and Mouse anti-Human CD3 antibody (PE) followed by Streptavidin (FITC).

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