anti-CD66e / CEA antibody
产品描述 | Rabbit Polyclonal antibody recognizes CD66e / CEA |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CD66e / CEA |
抗原物种 | Human |
抗原 | Recombinant protein corresponding to K35-N650 of Human CD66e / CEA. |
偶联标记 | Un-conjugated |
別名 | Carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; CD antigen CD66e; Carcinoembryonic antigen; Meconium antigen 100 |
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in EDTA buffer (pH 8.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
数据库连接 | Swiss-port # P06731 Human Carcinoembryonic antigen-related cell adhesion molecule 5 Swiss-port # Q3UKK2 Mouse Carcinoembryonic antigen-related cell adhesion molecule 5 |
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基因名称 | CEACAM5 |
全名 | carcinoembryonic antigen-related cell adhesion molecule 5 |
背景介绍 | This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
生物功能 | Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. [UniProt] |
细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
预测分子量 | 77 kDa |
翻译后修饰 | Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. [UniProt] |
ARG41923 anti-CD66e / CEA antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung cancer tissue. Antigen Retrieval: Heat mediation was performed in EDTA buffer (pH 8.0). The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG41923 anti-CD66e / CEA antibody at 1 µg/ml dilution, overnight at 4°C.
ARG41923 anti-CD66e / CEA antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse intestine tissue. Antigen Retrieval: Heat mediation was performed in EDTA buffer (pH 8.0). The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG41923 anti-CD66e / CEA antibody at 1 µg/ml dilution, overnight at 4°C.
ARG41923 anti-CD66e / CEA antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat intestine tissue. Antigen Retrieval: Heat mediation was performed in EDTA buffer (pH 8.0). The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG41923 anti-CD66e / CEA antibody at 1 µg/ml dilution, overnight at 4°C.