anti-CD69 antibody [FN50] (PE)

Key features and details

  • 产品描述: PE-conjugated Mouse Monoclonal antibody [FN50] recognizes CD69
  • 反应物种: Hu
  • 应用: FACS
  • 特异性: The clone FN50 recognizes CD69, an lymphocyte early activation marker. HLDA IV; WS Code A 91
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: FN50
  • 同位型: IgG1
  • 靶点名称: CD69
  • Brand:
CAT.NO. : ARG53891
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Product Details
概述
产品描述PE-conjugated Mouse Monoclonal antibody [FN50] recognizes CD69
反应物种Hu
应用FACS
特异性The clone FN50 recognizes CD69, an lymphocyte early activation marker.
HLDA IV; WS Code A 91
宿主Mouse
克隆Monoclonal
克隆号FN50
同位型IgG1
靶点名称CD69
抗原物种Human
抗原anti-µ-stimulated human B lymphocytes
偶联标记PE
別名GP32/28; Activation inducer molecule; MLR-3; BL-AC/P26; Leukocyte surface antigen Leu-23; AIM; Early activation antigen CD69; Early T-cell activation antigen p60; EA1; CD antigen CD69; CLEC2C; C-type lectin domain family 2 member C
应用说明
应用建议
应用推荐稀释比
FACS20 µl / 10^6 cells
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
缓冲液PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂15 mM Sodium azide
稳定剂0.2% (w/v) high-grade protease free BSA
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 969 Human CD69

Swiss-port # Q07108 Human Early activation antigen CD69

基因名称CD69
全名CD69 molecule
背景介绍CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.
生物功能Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. [UniProt]
研究领域Developmental Biology antibody; Immune System antibody
预测分子量23 kDa
翻译后修饰Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.
检测图片 (1)
  • ARG53891 anti-CD69 antibody [FN50] (PE) FACS image

    Flow Cytometry: Human PHA-activated peripheral blood stained with ARG53891 anti-CD69 antibody [FN50] (PE).

参考文献

克隆号文献

CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation.

Henderson NC et al.
J Biol Chem.,  (2004)

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Multiple dimeric forms of human CD69 result from differential addition of N-glycans to typical (Asn-X-Ser/Thr) and atypical (Asn-X-cys) glycosylation motifs.

Vance BA et al.
J Biol Chem.,  (1997)

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